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特色
描述
研究领域
Alzheimer's Disease, Cell Biology, Host Immune Response, Host-Virus Interaction, Inflammation, Inflammatory Mediators, Innate Immunity, NF-kB Signalling Pathway, Neuroscience, Obesity, RELA (p65), Virology
图片与验证
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Item 1 of 15
| 已测应用 | FC, ICC |
|---|---|
| 稀释范围 | ICC/IF=1:50-200, Flow-Cyt=1μg/Test |
| 反应性 | Human, Mouse |
| 预测反应性 | Bovine, Canine, Equine, Gallus, Porcine, Rabbit, Rat, Sheep, Zebrafish |
相关偶联物与制剂
−关键属性
−| 抗体类型 | Primary Antibody |
|---|---|
| 宿主 | Rabbit |
| 克隆性 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | KLH conjugated synthetic peptide derived from human NFKBp65 (51-100/551aa) |
| 靶点 | RELA |
| 分子量 | 61 kDa |
| 纯化 | Affinity purified by Protein A |
| 偶联 | Unconjugated |
储存与操作
−| 储存 | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| 形态/外观 | Liquid |
| 缓冲液/防腐剂 | 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 有效期 | 12 months from date of receipt. |
| 免责声明 | For research use only |
别名
−AIF3BL3; CMCU; NFKB3; p65; p65 NF-kappa B; p65 NFkB; NFkB; nos2; TF65_HUMAN; RELA; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; TF65_MOUSE; RELA proto-oncogene, NF-kB subunit; v-rel avian reticuloendotheliosis viral oncogene homolog A
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质量保证
Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.
常用数据库链接
基因符号
RELA
UniProt
UniProt 详情
−暂无 UniProt 数据
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Sahin Sultana, Biswadev Bishayi Neutralization of TNFR-1 and TNFR-2 modulates S. aureus induced septic arthritis by regulating the levels of pro inflammatory and anti inflammatory cytokines during the progression of the disease Immunology Letters, 196, 33 (2018)
应用
WB
反应性
Mouse
Rituparna Ghosh 1, Biswadev Bishayi 2 Neutralization of TLR2 in combination with either TNF-α or IL-1β antibody reduces the severity of septic arthritis through STAT3/mTOR signalling in lymphocytes Cell Immunol ., (2024)
应用
WB
反应性
Mouse
Sahin Sultana, Rajen Dey, Biswadev Bishayi Dual neutralization of TNFR-2 and MMP-2 regulates the severity of S. aureus induced septic arthritis correlating alteration in the level of interferon gamma and interleukin-10 in terms of TNFR2 blocking Immunologic Research, 66, 97 (2018)
应用
WB
反应性
Mouse
Bo Xiang, Ping Zhong, Lei Fang, Xianxian Wu, Yuqiang Song, Haicheng Yuan miR-183 inhibits microglia activation and expression of inflammatory factors in rats with cerebral ischemia reperfusion via NF-κB signaling pathway Experimental and Therapeutic Medicine, 18, 2540 (2019)
应用
WB
反应性
Rat
Sahin Sultana, Biswadev Bishayi Potential anti-arthritic and anti-inflammatory effects of TNF-α processing inhibitor-1 (TAPI-1): A new approach to the treatment of S. aureus arthritis Immunobiology, 225, 151887 (2019)
应用
WB
反应性
Mouse
Sahin Sultana, Rajen Dey, Biswadev Bishayi Role of plasminogen activator inhibitor – 1 (PAI-1) in regulating the pathogenesis of S. aureus arthritis via plasminogen pathway Immunology Letters, 209, 53 (2019)
应用
WB
反应性
Mouse
Song, Yong et al. NF κB expression increases and CFTR and MUC1 expression decreases in the endometrium of infertile patients with hydrosalpinx: a comparative study Reprod Biol Endocrinol, 10, 86 (2012)
