5-Heneicosylresorcinol

SKU: orb1683443

描述

This research compound, 5-heneicosylresorcinol, exhibits anti-allergic activity by inhibiting β-hexosaminidase release in RBL-2H3 cells and anti-adipogenic effects by reducing triglyceride accumulation in 3T3-L1 cells. It also demonstrates nematicidal activity against P. redivivus, C. elegans, and B. xylophilus.

研究领域

Immunology & Inflammation, Infectious Disease & Virology

图片与验证

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关键属性

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CAS 号	70110-59-7
MW	404.67
纯度	98.00% (May vary between batches)
分子式	C₂₇H₄₈O₂
SMILES	CCCCCCCCCCCCCCCCCCCCCc1cc(O)cc(O)c1
靶点	Antifungal,Antifection,NADPH-oxidase

生物活性

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体外

Alkylresorcinols are phenolic lipids present at levels of 0.03-0.15% in wheat and rye grains and almost 10 times higher in respective bran products. Despite numerous studies on the influence of dietary fibers on the regulation of energy metabolism, this issue still remains controversial. METHODS AND RESULTS: The objective of our current studies was to investigate whether 5-n-alk(en)ylresorcinols, natural phenolic components of high fiber human diets, may be considered as natural regulators of excessive fat accumulation. Our studies revealed that 5-n-alk(en)ylresorcinols isolated from wheat and rye bran inhibit glycerol-3-phosphate dehydrogenase, the key enzyme in triglyceride synthesis in adipocytes, specifically and effectively. Further in vitro studies showed that these compounds also prevent triglyceride accumulation in 3T3-L1 cells. CONCLUSIONS: The most effective compound in both systems was 5-n-heneicosylresorcinol(5-Heneicosylresorcinol). The results indicate that the potential to prevent triglyceride accumulation increases with the hydrophobicity of the phenolic inhibitor.

储存与操作

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储存	-20°C
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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5 Heneicosylresorcinol, 5Heneicosylresorcinol, 5-Heneicosylresorcinol, Antifection, antifungal, cereals, inhibit, Inhibitor, microscale amended medium assay, NADPH-oxidase, NADPHoxidase, Fungal, Fusarium oxysporum, supervised metabolite profiling

质量保证

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化合物标识

PubChem CID

155461 ↗

关键属性

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暂无计算属性。

实验方案信息

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5-Heneicosylresorcinol

描述

研究领域

图片与验证

关键属性

生物活性

储存与操作

别名

质量保证

化合物标识

关键属性

实验方案信息

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