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AICAR phosphate

SKU: orb1707700

描述

AICAR phosphate

研究领域

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

图片与验证

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关键属性

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CAS 号681006-28-0
MW356.228
纯度>99.99% (May vary between batches)
分子式C9H14N4O5.xH3O4P
SMILESO[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(N)=C(C(N)=O)N=C2.P(=O)(O)(O)O xH3O4P
靶点Endogenous Metabolite,Mitophagy,AMPK,NOS,YAP,Autophagy
溶解性DMSO:75 mg/mL;H2O:80 mg/mL;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL

生物活性

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体内
Male 5-week-old ZDF rats were either subcutaneously injected with a single dose of AICAR phosphate (0.5 mg/g) or subjected to a single bout of treadmill running. The results showed that compared to untreated control ZDF rats, both the exercise group and the rats receiving AICAR phosphate injection exhibited significantly increased AMPK-α2 activity in the white gastrocnemius muscle.
体外
HepG2 cells were treated with different concentrations of AICAR phosphate (0.1-1.0 mM) for 12, 24, and 48 hours, respectively. The final results demonstrated that AICAR phosphate reduced the expression of the insulin receptor protein.

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only

别名

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YAP, iNOS, Mitophagy, Acadesine phosphate, AICA Riboside phosphate, Autophagy, AMPK

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质量保证

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关键属性

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实验方案信息

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25 mg
¥ 1,170.00
发货Usually dispatched within 5-10 working days
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