CD18 Antibody

SKU: orb154416

描述

Mouse monoclonal antibody to CD18 which belongs to the integrin beta chain family. Defects in ITGB2 are the cause of leukocyte adhesion deficiency type 1 (LAD1). CD18 is involved in cellular adhesion and the immune response. CD18 and the a subunits are expressed broadly by all leukocytes with NK and T cells showing higher density of surface expression.

研究领域

Immunology & Inflammation

图片与验证

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已测应用	FC, Functional Studies, IHC-Fr, IHC-P, IP, WB
反应性	Human
应用说明	Functional application: The antibody MEM-48 induces high-affinity conformation of LFA-1 complex. Western blotting: Recommended dilution: 1-2 μg/ml.Flow cytometry: Recommended dilution: 2 μg/ml. Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/ml; positive tissue: spleen, microglia.

关键属性

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抗体类型	Primary Antibody
克隆性	Monoclonal
同种型	Mouse IgG1
克隆号	MEM-48
免疫原	Leukocytes of a patient suffering from a LGL-type leukemia.
靶点	CD18
纯化	Purified by sequential steps of physicochemical fractionation (caprylic acid precipitation and ammonium sulfate precipitation).
偶联	Unconjugated

储存与操作

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储存	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂	Phosphate buffered saline (PBS), pH 7.4
浓度	1 mg/ml
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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Integrin beta2, Complement receptor C3 subunit beta, ITGB2

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质量保证

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