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CD261 Antibody

SKU: orb154377

描述

Mouse monoclonal antibody to CD261 which is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to activated CD261 which is expressed in most human tissues including spleen, peripheral blood leucocytes, thymus and in a variety oFT tumour-derived cell lines. It plays a role in inducing cell death. The binding oFT TRAIL to DR4 triggers the activation oFT pro-caspases 8 and 10, leading to apoptosis.

研究领域

Immunology & Inflammation; Cell Biology

图片与验证

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已测应用FC, ICC, IP
反应性Human
应用说明
Flow cytometry: Recommended dilution: 1-4 μg/ml.

关键属性

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抗体类型Primary Antibody
克隆性Monoclonal
同种型Mouse IgG1
克隆号DR-4-02
免疫原Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1.
靶点CD261
纯化Purified by protein-A affinity chromatography.
偶联Unconjugated

储存与操作

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储存Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
浓度1 mg/ml
有效期12 months from date of receipt.
免责声明For research use only

别名

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DR4, APO2, TNFRSF10A, TRAILR1, TRAIL-R1

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质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

UniProt 详情

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暂无 UniProt 数据

NCBI 基因详情

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暂无 NCBI 基因数据

实验方案信息

FC
流式细胞术
查看实验方案
ICC
免疫细胞化学
查看实验方案
IP
免疫沉淀
查看实验方案

可选规格

请在下方选择规格

0.1 mg
¥ 4,810.00
免费二抗(20 µl)0/0

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发货Usually dispatched within 5-10 working days weeks.
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