AVS Bio - Human ACE-2

SKU: A005

特色

描述

Human ACE-2 (angiotensin-converting enzyme 2) belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus)

研究领域

Hematology, Infectious Disease & Virology

图片与验证

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应用说明	The protein is produced in HEK293 cells and does not contain a tag. It was purified to homogeneity (figure 1). The calculated molecular weight of recombinant hACE-2-is 70.4 kDa.

关键属性

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蛋白序列	Non-reduced
内毒素	<0.11 EU/ml

储存与操作

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储存	The product should be stored at - 80°C (stable for at least 1 year). The buffer contains PBS without preservative. After thawing it should be stored in appropriate small aliquots at - 20°C or - 80°C (stable for at least 2 months).
形态/外观	solution
缓冲液/防腐剂	1.59 mg/ml in PBS
浓度	1.59 mg/ml, 22.6 µM
有效期	For shelf life and expiration details, please refer to the Certificate of Analysis (CoA).
干冰运输	请注意：本产品需要干冰运输，将收取干冰附加费。
免责声明	For research use only

相似产品

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Item 1 of 2
AVS Bio - Human ACE-2-(TEV-Fc)C [A004]
可选规格： 100 μg

质量保证

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实验方案信息

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