AVS Bio - Monoclonal Human Anti-WD repeat containing protein 5 (WDR5) immunoglobulin

SKU: MQR2.1301

特色

描述

Antibody against WD repeat-containing protein 5, which contributes to histone modification. It may position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation

图片与验证

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已测应用	ChIP-qPCR, ELISA, IP
稀释范围	ELISA: 1:5000 – 1:25000 IP: 2 µg/ml Unless the stability in the actual test system has been established, it is recommended to dilute the product immediately before use.
反应性	Human

关键属性

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克隆性	Monoclonal
同种型	Human IgG1, κ
免疫原	Full-length human WD repeat domain5
靶点	WD repeat-containing protein 5 (WDR5)
纯化	Protein A purified.
偶联	Unconjugated

储存与操作

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储存	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
形态/外观	solution
缓冲液/防腐剂	The antibody is supplied in PBS.
有效期	For shelf life and expiration details, please refer to the Certificate of Analysis (CoA).
干冰运输	请注意：本产品需要干冰运输，将收取干冰附加费。
免责声明	For research use only

质量保证

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