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Recombinant Beta Catenin Antibody / Rabbit Monoclonal

SKU: orb2640857

描述

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]

图片与验证

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已测应用IHC-P
稀释范围The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
反应性Human
应用说明
Titration of the recombinant beta Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

关键属性

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抗体类型Primary Antibody
宿主Rabbit
克隆性Recombinant
同种型Rabbit IgG, kappa
克隆号CTNB1-1R
免疫原Beta Catenin protein was used as the immunogen for the recombinant beta Catenin antibody.
纯化Protein A affinity chromatography
偶联Unconjugated

储存与操作

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储存Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
有效期12 months from date of receipt.
免责声明For research use only

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  • Recombinant Beta Catenin Antibody / Rabbit Monoclonal [orb2640858]

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质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

UniProt 详情

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暂无 UniProt 数据

实验方案信息

IHC-P
石蜡切片免疫组化
查看实验方案

可选规格

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7 ml
¥ 9,750.00
免费二抗(20 µl)0/0

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发货Usually dispatched within 5-10 working days
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