Recombinant CD137 Antibody / 4-1BB / TNFRSF9

SKU: orb2643748

描述

CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.

研究领域

Immunology & Inflammation

图片与验证

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已测应用	IHC-P, WB
稀释范围	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Western blot: 2-4ug/ml
反应性	Human
应用说明	Optimal dilution of the recombinant CD137 antibody should be determined by the researcher.

关键属性

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抗体类型	Primary Antibody
宿主	Mouse
克隆性	Recombinant
同种型	Rabbit IgG, kappa
克隆号	4-1BB/4552R
免疫原	A human CD137 protein fragment within amino acids 19-188 was used as the immunogen for the recombinant CD137 antibody.
纯化	Protein A affinity chromatography
偶联	Unconjugated

储存与操作

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储存	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂	1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
有效期	12 months from date of receipt.
免责声明	For research use only

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质量保证

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