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CD16 Antibody

SKU: orb749494
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描述

Recognizes a protein of 50-65 kDa, identified as CD16 (Workshop IV; Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This mAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.

研究领域

Immunology & Inflammation

图片与验证

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已测应用FACS, Functional Studies, IF
稀释范围Functional studies (order BSA/sodium azide-free format),Flow cytometry: 1-2ug/10^6 cells,Immunofluorescence: 1-2ug/ml
反应性Human
应用说明
Optimal dilution of the CD16 antibody should be determined by the researcher.

关键属性

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抗体类型Primary Antibody
宿主Mouse
克隆性Monoclonal
同种型Mouse IgG2a, kappa
克隆号HuNK2
免疫原Human peripheral blood lymphocytes from a NK-leukemia patient were used as the immunogen for the CD16 antibody.
纯化Protein G affinity chromatography
偶联Unconjugated

储存与操作

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储存Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
有效期12 months from date of receipt.
免责声明For research use only

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    CD16 Rabbit Polyclonal Antibody [orb101668]

    WB

    Human

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    Polyclonal

    Unconjugated

    50 μl, 100 μl, 200 μl
质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

常用数据库链接

UniProt
P08637

UniProt 详情

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暂无 UniProt 数据

实验方案信息

FACS
荧光激活细胞分选（FACS，流式细胞术）
查看实验方案
IF
免疫荧光
查看实验方案
查看更多实验方案

可选规格

请在下方选择规格

20 μg
¥ 4,810.00
100 μg
¥ 9,750.00
选择偶联或无载体版本
免费二抗（20 µl）0/0

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发货Usually dispatched within 5-10 working days
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