CDH1 (C2) Antibody, Rabbit Polyclonal

SKU: orb66765

描述

Rabbit polyclonal to CDH1.Cadherin-1 (CDH1) is a single-pass membrane protein. Cadherins are calcium-dependent celladhesion proteins. They preferentially interact with themselves in a homophilic manner in connectingcells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved inmechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. It has a potentinvasive suppressor role. It is a ligand for integrin alpha-E/beta-7. Defects in CDH1 are the cause ofhereditary diffuse gastric cancer (HDGC) and are a cause of susceptibility to endometrial cancer(ENDMC) and ovarian cancer (OC).

研究领域

Epigenetics & Chromatin

图片与验证

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已测应用	WB
稀释范围	WB:1:500-1:1000
反应性	Human

关键属性

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宿主	Rabbit
克隆性	Polyclonal
免疫原	C-terminal region of human CDH1
分子量	97
纯度	Affinity purification
偶联	Unconjugated

储存与操作

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储存	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂	0.01% NaN3
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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anti-CDH1 antibody,anti-Cadherin1 antibody,anti-CAM 120 antibody,anti-80 antibody,anti-Epithelial cadherin antibody,anti-Ecadherin antibody,anti-Uvomorulin antibody,anti-CD324 antibody,anti-CDHE antibody,anti-UVO antibody

质量保证

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