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Cholesteryl Hemisuccinate

SKU: orb1745228

描述

Cholesteryl Hemisuccinate is a water-soluble cholesterol derivative with hepatoprotective and anticancer properties. It is used in research to study mechanisms against drug-induced liver injury (e.g., acetaminophen) and to investigate inhibition of DNA polymerases and topoisomerases in vitro, impacting cell replication and repair pathways.

研究领域

Cell Biology, Molecular Biology

图片与验证

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关键属性

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CAS 号1510-21-0
MW486.73
纯度99.98% (May vary between batches)
分子式C31H50O4
SMILES[H][C@@]12CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OC(=O)CCC(O)=O
靶点DNA/RNA Synthesis,Necroptosis,Topoisomerase,Apoptosis
溶解性10% EtOH+90% Corn Oil:2 mg/mL (4.11 mM);Ethanol:22.5 mg/mL (46.23 mM);DMSO:10 mg/mL (20.55 mM)

生物活性

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体内
Cholesteryl Hemisuccinate (100 mg/kg ; ip ; single administration before AAP) eliminated AAP-induced apoptosis and necrosis in ICR mice (CD-1) for histological and biochemical diagnosis.
体外
Cholesteryl Hemisuccinate (0-1000 μM) inhibited the growth of MCF-7 and MCF-10A cells.

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only

别名

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Cholesterol hydrogen succinate, Cholesterol hydrogen Succinate, Cholesteryl, Cholesteryl Hemisuccinate, DNA polymerase, DNA Synthesis, DNASynthesis, Apoptosis, Topo, RNA Synthesis, RNASynthesis

相似产品

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    C31H50O4

    500 mg, 1 g, 100 mg
质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

关键属性

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暂无计算属性。

实验方案信息

可选规格

请在下方选择规格

500 mg
¥ 1,040.00
1 ml x 10 mM (in DMSO)
¥ 1,040.00
1 g
¥ 1,170.00
5 g
¥ 2,470.00
发货Usually dispatched within 5-10 working days
批量询价