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DBPR112 HCl

SKU: orb1739982

描述

DBPR112 is a clinical candidate EGFR inhibitor with potent activity against resistant mutations, including L858R/T790M and exon 20 insertions, outperforming osimertinib in vitro. It demonstrates favorable oral pharmacokinetics, significant in vivo antitumor efficacy in xenograft models, and a promising safety profile for non-small cell lung cancer research.

图片与验证

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关键属性

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CAS 号2889316-21-4
MW570.08
分子式C32H32ClN5O3
SMILESN([C@H](CO)C1=CC=CC=C1)C2=C3C(=C(OC3=NC=N2)C4=CC=CC=C4)C5=CC(NC(/C=C/CN(C)C)=O)=CC=C5.Cl
靶点Others

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only
质量保证

质量保证

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关键属性

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实验方案信息

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