DMG-PEG 2000

SKU: orb1298372

描述

DMG-PEG2000 is a lipid-PEG conjugate used to formulate lipid nanoparticles (LNPs) for nucleic acid delivery. It enhances mucus penetration for oral plasmid DNA delivery in vivo and improves the transfection efficiency of siRNA-loaded liposomes in both in vitro and in vivo research applications.

研究领域

Metabolism Research

图片与验证

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关键属性

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CAS 号	160743-62-4
MW	2526
纯度	≥98% (May vary between batches)
分子式	(C₂H₄O)nC₃₂H₆₂O₅
SMILES	N.CCCCCCCCCCCCCC(=O)OCC(COCCOC)OC(=O)CCCCCCCCCCCCC
靶点	Others,Liposome
溶解性	Ethanol:100 mg/mL (39.59 mM);DMSO:60 mg/mL (23.75 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (0.79 mM)

客户验证数据

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以下数据由各地研究人员提交。即使我们尚未自行检测，这些结果也有助于判断该产品是否适合您的应用或种属。

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反应性分布

最新实验

3 Results

稀释

样本

摘要

In vitro

Rat

Lipid nanoparticles (LNPs)

DMG-PEG 2000 is used as a...

In vitro

Mouse

Lipid nanoparticles (LNPs)

DMG-PEG 2000 is used as a...

In vivo

Mouse

Lipid nanoparticles (LNPs)

DMG-PEG 2000 is used as a...

生物活性

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体内

METHODS: To study the permeability of NP-3, a single dose of NP-3 (150 μg DNA per mouse) was administered orally to mice. RESULTS: The NP-3 group maintained high luciferase expression in the liver, lung, and intestinal regions within 12 to 24 hours after administration. In addition, NP-3 showed a 1.5-fold higher signal intensity than the NP-1 or NP-2 groups within 12 to 24 hours after oral administration.

储存与操作

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储存	-20°C
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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therapy, T2D, type II diabete, 293T, A549, DMG PEG 2000, DMGPEG 2000, DMG-PEG 2000, DMG-PEG2000, DMG-PEG-2000, HeLa, HepG2, Inhibitor, inhibit, lPEI/DNA nanoparticle, nucleic acid

相似产品

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DMG-PEG-Mal (MW 2000) [orb3027025]
MW:
2000 (Average)
可选规格： 50 mg, 25 mg, 10 mg
DMG-PEG-SH (MW 2000) [orb3137315]
可选规格： 50 mg, 10 mg
DMG-PEG-OH (MW 2000) [orb3137343]
可选规格： 10 mg, 50 mg, 25 mg, 5 mg, 1 mg
DMG-PEG-NHS, MW 2000 [orb3026245]
可选规格： 10 mg, 50 mg

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

化合物标识

PubChem CID

155819508 ↗

关键属性

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暂无计算属性。

实验方案信息

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DMG-PEG 2000

描述

研究领域

图片与验证

关键属性

客户验证数据

按应用统计成功数

反应性分布

最新实验

生物活性

储存与操作

别名

相似产品

DMG-PEG-Mal (MW 2000) [orb3027025]

DMG-PEG-SH (MW 2000) [orb3137315]

DMG-PEG-OH (MW 2000) [orb3137343]

DMG-PEG-NHS, MW 2000 [orb3026245]

质量保证

化合物标识

关键属性

实验方案信息

可选规格