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EGR2 (C) Antibody, Rabbit Polyclonal

SKU: orb131906
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描述

Rabbit polyclonal to EGR2. E3 SUMO-protein ligase EGR2 belongs to the EGR C2H2-type zinc-finger protein family. EGR2 is a sequence-specific DNA-binding transcription factor and binds to two specific DNA sites located in the promoter region of HOXA4. EGR2 helps SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Defects in EGR2 are a cause of congenital hypomyelination neuropathy (CHN), of Charcot-Marie-Tooth disease type 1D (CMT1D), and of Dejerine-Sottas syndrome (DSS).

研究领域

Neuroscience

图片与验证

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已测应用ChIP, IP, WB
稀释范围WB:1:1000-1:3000,IF/ICC:1:100-1:200
反应性Human, Mouse
应用说明
WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.

Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human EGR2.

关键属性

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宿主Rabbit
克隆性Polyclonal
免疫原C-terminal region of human EGR2
分子量Predicted M.W.: 50kDa, Observed M.W.: 60 kDa
纯度Affinity purification
纯化Purified by affinity purification using immunogen.
偶联Unconjugated

储存与操作

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储存Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂1 x PBS (pH 7.4), 100 ug/ml rAlbumin, 40% Glycerol, 0.01% NaN3
浓度100 μg/ml BSA
有效期12 months from date of receipt.
免责声明For research use only

别名

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anti E3 SUMO-protein ligase EGR2 antibody, anti AT591 antibody, anti Early growth response protein 2 antibody, anti Zinc finger protein Krox-20 antibody, anti EGR-2 antibody, anti KROX20 antibody

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  • EGR2 Rabbit Polyclonal Antibody (Biotin)

    EGR2 Rabbit Polyclonal Antibody (Biotin) [orb2065819]

    IHC,  WB

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质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

常用数据库链接

UniProt
P11161

UniProt 详情

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暂无 UniProt 数据

实验方案信息

WB
免疫印迹（WB）
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IP
免疫沉淀
查看实验方案
ChIP
染色质免疫沉淀（ChIP）
查看实验方案
查看更多实验方案

按应用筛选

按种属筛选

Chengyun Xu et al. Early growth response 2 as a target of IL-13/STAT6 signaling induces the goblet cell metaplasia of allergic airway epithelia Allergol Int, (2026)

PubMed: 41708397

应用

IP

反应性

Human

可选规格

请在下方选择规格

100 μl
¥ 7,020.00
选择偶联或无载体版本
免费二抗（20 µl）0/0

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发货Usually dispatched within 5-10 working days.
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