ELMO1 (vPairTM) Antibodies

SKU: orb131825

描述

Rabbit polyclonal to ELMO1. ELMO1 antibodies represent a pair of fully characterized antibodies that recognize two different regions of a target protein. The product is developed by Biorbyt to address whether the signal observed truly represents the protein of interest, an often encountered issue in antibody pairs-based assays. The use of a pair of fully characterized vPair antibodies in the same assay can validate signal specificity since vPair antibodies recognize two independent epitopes of the same protein. Different sets of vPair antibodies are developed at Biorbyt to work with specific applications, including antibody pairs arrays, Western blot, IP-Western, ChIP, IHC, and FACS. Engulfment and cell motility protein 1 (ELMO1) is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. ELMO1 acts in assocation with DOCK1 and CRK. ELMO1 was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. Furthermore, ELMO1 may enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

研究领域

Cell Biology

图片与验证

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已测应用	WB
稀释范围	WB:1:1000-1:3000
应用说明	WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications. Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with GST-fusion proteins containing either the N-terminal or the C-terminal region of human ELMO1.

关键属性

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宿主	Rabbit
克隆性	Polyclonal
免疫原	N-terminal or the C-terminal region of human ELMO1
分子量	84
纯度	Affinity purification
偶联	Unconjugated

储存与操作

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储存	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂	0.01% NaN3
浓度	100 μg/ml BSA
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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anti Engulfment and cell motility protein 1 antibody pairs, anti Protein ced-12 homolog antibody pairs

质量保证

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