EpCAM Antibody / Extracellular domain

SKU: orb2640159

描述

EpCAM (Epithelial Cell Adhesion Molecule), also known as CD326, plays a crucial role in various cellular processes and has been linked to the development and progression of cancer. EpCAM is a transmembrane glycoprotein that is expressed in high levels on the surface of epithelial cells. In cancer cells, the expression of EpCAM is often upregulated, leading to increased cell proliferation, invasion, and metastasis. Studies have shown that high levels of EpCAM are associated with poor prognosis in various types of cancer, including breast, colon, and lung cancer. The overexpression of EpCAM in cancer cells makes it an attractive target for diagnostic and therapeutic purposes. Researchers are exploring the use of EpCAM as a biomarker for early cancer detection through blood tests and imaging techniques. In addition, EpCAM-targeted therapies, such as monoclonal antibodies and immunotherapies, are being developed to specifically target and kill cancer cells that overexpress EpCAM.

研究领域

Immunology & Inflammation

图片与验证

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已测应用	ELISA, IF, IHC-P, WB
稀释范围	ELISA: order BSA/sodium azide-free format for coating,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Western blot: 1-2ug/ml
反应性	Canine, Feline, Guinea pig, Human
应用说明	Titering of the EpCAM antibody may be required for optimal performance.

关键属性

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抗体类型	Primary Antibody
宿主	Mouse
克隆性	Monoclonal
同种型	Mouse IgG
克隆号	EGP40/1384
免疫原	A human partial recombinant protein corresponding to amino acids 100-224 (extracellular domain) was used as the immunogen for the EpCAM antibody.
纯化	Protein G affinity chromatography
偶联	Unconjugated

储存与操作

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储存	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂	1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
有效期	12 months from date of receipt.
免责声明	For research use only

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应用：
FACS, IF, IHC-P, WB
反应性：
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种属/宿主：
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可选规格： 100 μg, 20 μg
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EpCAM Antibody / Extracellular domain [orb2640454]
应用：
FACS, IF, IHC-P, WB
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EpCAM Rabbit Polyclonal Antibody [orb1294311]
应用：
FC, IF, IHC, WB
反应性：
Human, Mouse
种属/宿主：
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克隆性：
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偶联：
Unconjugated
可选规格： 100 μl, 25 μl
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Recombinant EpCAM Antibody / Extracellular domain [orb606388]
应用：
IHC-P, WB
反应性：
Canine, Feline, Human
种属/宿主：
Rabbit
克隆性：
Recombinant
偶联：
Unconjugated
可选规格： 100 μg, 20 μg
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EpCAM Antibody / Extracellular domain [orb750043]
应用：
ELISA, IF, IHC-P, WB
反应性：
Canine, Feline, Guinea pig, Human
种属/宿主：
Mouse
克隆性：
Monoclonal
偶联：
Unconjugated
可选规格： 100 μg, 20 μg

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.