Fluoxetine HCl

SKU: orb1310602

特色

描述

Fluoxetine hydrochloride (Lilly 110140) is a selective serotonin reuptake inhibitor (SSRI) used as an antidepressant with a favorable side-effect profile. It is widely employed in neuroscience research to study serotonin neurotransmission in both in vitro binding assays and in vivo behavioral models of depression.

研究领域

Neuroscience, Stem Cell & Developmental Biology

图片与验证

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关键属性

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CAS 号	56296-78-7
MW	345.79
纯度	>98%
分子式	C₁₇H₁₈F₃NO ∙ HCl
SMILES	Cl.CNCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1
靶点	Monoamine transporter
溶解性	Soluble in DMSO (up to 35 mg/ml) or in Water (up to 4 mg/ml)

生物活性

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体内	Fluoxetine accelerates the maturation of immature neurons. It enhances the proliferation of new cells in the dentate gyrus of the adult rat hippocampus, strengthens neurodependent long-term potentiation in the hippocampal dentate gyrus, and increases the number of proliferating cells in the prefrontal cortex.
体外	When co-administered in adult male SD rats, fluoxetine and olanzapine induce a robust and sustained increase in extracellular dopamine levels, with concentrations surpassing baseline by 361% and 272%, respectively—significantly higher than when either drug is used alone. Additionally, fluoxetine reverses the prolonged latency of escape caused by unavoidable shocks in adult male SD rats.

储存与操作

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储存	RT
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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LY-110,140

相似产品

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Norfluoxetine HCl [orb1306473]
纯度：
>98%
CAS 号：
57226-68-3
MW:
331.8
分子式：
C₁₆H₁₆F₃NO HCl
可选规格： 5 mg, 25 mg
Fluoxetine hydrochloride [orb1224654]
纯度：
>98% (HPLC)
CAS 号：
56296-78-7
MW:
345.79
分子式：
C₁₇H₁₈F₃NO·HCl
可选规格： 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Fluoxetine HCl [orb3012993]
纯度：
≥98% (HPLC); NMR (Conforms)
CAS 号：
56296-78-7
MW:
345.8
分子式：
C₁₇H₁₈F₃NO • HCl
可选规格： 100 mg, 1 g

质量保证

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化合物标识

PubChem CID

62857 ↗

关键属性

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暂无计算属性。

实验方案信息

查看更多实验方案

纯度：	>98%
CAS 号：	57226-68-3
MW:	331.8
分子式：	C₁₆H₁₆F₃NO HCl

纯度：	>98% (HPLC)
CAS 号：	56296-78-7
MW:	345.79
分子式：	C₁₇H₁₈F₃NO·HCl

纯度：	≥98% (HPLC); NMR (Conforms)
CAS 号：	56296-78-7
MW:	345.8
分子式：	C₁₇H₁₈F₃NO • HCl

Fluoxetine HCl

描述

研究领域

图片与验证

关键属性

生物活性

储存与操作

别名

相似产品

Norfluoxetine HCl [orb1306473]

Fluoxetine hydrochloride [orb1224654]

Fluoxetine HCl [orb3012993]

质量保证

化合物标识

关键属性

实验方案信息

可选规格