购物车摘要

购物车里还没有商品。

GDC0575 monohydrochloride

SKU: orb1305087

描述

GDC-0575 monohydrochloride (ARRY-575) is a highly potent and selective Chk1 inhibitor (IC50 = 1.2 nM). It disrupts Chk1-mediated cell cycle checkpoints, forcing DNA-damaged cells into mitosis. This mechanism is applied in preclinical cancer research, particularly in combination with DNA-damaging agents, to study chemosensitization in vitro and in vivo models.

研究领域

Cell Biology

图片与验证

−

关键属性

−
CAS 号1196504-54-7
MW414.73
纯度97.85% (May vary between batches)
分子式C16H21BrClN5O
SMILESO=C(C1CC1)NC2=CNC3=NC=C(Br)C(N4C[C@H](N)CCC4)=C32.[H]Cl
靶点Chk
溶解性DMSO:60 mg/mL (144.67 mM)

生物活性

−
靶点 IC50
Chk1:1.2 nM

储存与操作

−
储存-20°C
有效期12 months from date of receipt.
免责声明For research use only

别名

−
Chk1, ARRY575, ARRY-575, ARRY 575, GDC 0575, GDC 0575 Monohydrochloride, GDC0575, GDC-0575, GDC0575 Monohydrochloride, GDC0575 monohydrochloride, GDC-0575 Monohydrochloride, GDC-0575 monohydrochloride
质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

关键属性

−
暂无计算属性。

实验方案信息

可选规格

请在下方选择规格

1 mg
¥ 1,040.00
2 mg
¥ 1,300.00
5 mg
¥ 1,560.00
1 ml x 10 mM (in DMSO)
¥ 1,690.00
10 mg
¥ 1,950.00
25 mg
¥ 3,120.00
50 mg
¥ 4,290.00
100 mg
¥ 5,720.00
200 mg
¥ 8,060.00
发货Usually dispatched within 5-10 working days
批量询价