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Gramicidin

SKU: orb1226342

描述

A group of peptide antibiotics from bacillus brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is one of the two principal components of tyrothricin.(In Vitro):Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. There is poor Gramicidin activity against E. coli and S. cerevisae as shown from the survival of microbes (%) over a range of Gramicidin concentrations, in contrast with the action of Gramicidin on S. aureus. The microbicidal activity occurs over a range of low Gramicidin and DODAB concentrations which are not toxic to S. cerevisae.

图片与验证

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关键属性

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CAS 号1405-97-6
MW1882.34
纯度>98% (HPLC)
分子式C99H140N20O17
SMILESCC(C)CC(C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(C)C)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC(C)C)C(=O)NC(CC5=CNC6=CC=CC=C65)C(=O)NC(CC(C)C)C(=O)NC(CC7=CNC8=CC=CC=C87)C(=O)NCCO)NC(=O)C(C)NC(=O)CNC(=O)C(C(C)C)NC=O
靶点MRP
溶解性DMSO: 10 mM

生物活性

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体外
Gramicidin is an antimicrobial peptide assembling as channels in membranes and increasing their permeability towards cations. There is poor Gramicidin activity against E. coli and S. cerevisae as shown from the survival of microbes (%) over a range of Gramicidin concentrations, in contrast with the action of Gramicidin on S. aureus. The microbicidal activity occurs over a range of low Gramicidin and DODAB concentrations which are not toxic to S. cerevisae.

储存与操作

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储存Storage temperature: -20°C. Stability: ≥ 2 years
有效期12 months from date of receipt.
免责声明For research use only

别名

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Gramicidin | MDL MFCD00131232 | EINECS 215-790-4

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质量保证

质量保证

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实验方案信息

可选规格

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500 mg
25 mg
¥ 1,170.00
50 mg
¥ 1,300.00
100 mg
¥ 1,560.00
200 mg
¥ 2,080.00