JP-11646

SKU: orb2279720

描述

JP-11646 is a novel potent, selective, non-ATP competitive Pim2 inhibitor with IC50 of 0.5/1/24 nM for Pim2/3/1, respectively; shows less potency for other kinases in a kinase selectivity panel; exhibits 4-760-fold greater suppression of MM proliferation and viability than ATP-competitive PIM inhibitors; significant reduces tumor burden and increases median survival in xenogeneic myeloma murine models.

图片与验证

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关键属性

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CAS 号	1902983-63-4
纯度	0.98

储存与操作

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有效期	12 months from date of receipt.
免责声明	For research use only

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实验方案信息

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