LO-3-63

SKU: orb3135894

描述

LO-3-63 is a Ribociclib analogue featuring a truncated fumaramide group and acts as a CDK4/6 degrader with PROTAC properties. It degrades CDK4/6 in cells via a CUL4DCAF16-dependent pathway.

研究领域

Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry

图片与验证

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关键属性

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靶点	E1/E2/E3 Enzyme,CDK,PROTACs

储存与操作

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储存	-20°C
有效期	12 months from date of receipt.
免责声明	For research use only

质量保证

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常用数据库链接

基因符号

E1/E2/E3 Enzyme,CDK,PROTACs

实验方案信息

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