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MK-4827 Racemate

SKU: orb1305758

描述

MK-4827 Racemate (Niraparib Racemate) is a potent and selective inhibitor of PARP1 and PARP2, exhibiting IC50 values of 3.8 nM and 2.1 nM, respectively. It shows over 330-fold selectivity against PARP3, V-PARP, and Tank1. This compound is widely used in cancer research, particularly for studying DNA damage response and synthetic lethality in both cellular and animal models of BRCA-mutant cancers.

研究领域

Epigenetics & Chromatin, Molecular Biology

图片与验证

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关键属性

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CAS 号1038915-75-1
MW320.39
纯度99.86% (May vary between batches)
分子式C19H20N4O
SMILESNC(=O)c1cccc2cn(nc12)-c1ccc(cc1)C1CCCNC1
靶点PARP
溶解性DMSO:60 mg/mL (187.27 mM)

生物活性

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靶点 IC50
PARP2:2.1 nM|PARP1:3.8 nM

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only

别名

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Niraparib Racemate, MK4827 Racemate, MK-4827 Racemate, PARP1, PARP2, MK 4827 Racemate, 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide
质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

关键属性

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暂无计算属性。

实验方案信息

可选规格

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1 mg
¥ 1,170.00
2 mg
¥ 1,430.00
5 mg
¥ 1,690.00
1 ml x 10 mM (in DMSO)
¥ 2,210.00
10 mg
¥ 2,600.00
25 mg
¥ 4,420.00
50 mg
¥ 7,280.00
100 mg
¥ 9,620.00
发货Usually dispatched within 5-10 working days
批量询价