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MRS8454

SKU: orb3173615

描述

MRS8454 is a positive allosteric modulator (PAM) of the A3 adenosine receptor (A3AR). It significantly enhances the maximal effect of the standard agonist Cl-IB-MECA to approximately 286%-300% and notably decreases its EC50 value. MRS8454 effectively augments the ability of A3AR agonists to inhibit forskolin-induced cAMP accumulation and can be utilized in the development of molecular probes.

研究领域

Neuroscience, Pharmacology & Drug Discovery

图片与验证

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关键属性

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靶点Adenosine Receptor

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only
质量保证

质量保证

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实验方案信息

可选规格

请在下方选择规格

50 mg
10 mg