购物车摘要

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N3-PEG3-vc-PAB-MMAE

SKU: orb1987912

描述

This ADC drug-linker conjugate incorporates the potent tubulin inhibitor MMAE via a cleavable valine-citrulline linker and a triethylene glycol spacer. It is widely used in preclinical research for constructing antibody-drug conjugates to evaluate their antitumor efficacy in both in vitro cytotoxicity assays and in vivo xenograft models.

研究领域

Cell Biology, Pharmacology & Drug Discovery

图片与验证

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关键属性

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MW1352.66
分子式C67H109N13O16
SMILESCC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCN=[N+]=[N-])=O)=O)=O)C=C3)=O)C)=O)=O)C
靶点PROTAC Linker,Drug-Linker Conjugates for ADC

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only

相似产品

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  • N3-PEG3-vc-PAB-MMAE [orb1473155]

    >98%

    1352.66

    C67H109N13O16

    10 mg
质量保证

质量保证

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关键属性

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实验方案信息

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100 mg
500 mg