Osimertinib dimer

SKU: orb3135414

描述

Osimertinibdimer is the dimer of Osimertinib. Osimertinib (AZD9291) is a covalent, orally active, irreversible, and mutation-selective EGFR inhibitor, effectively suppressing L858R (IC50=12 nM) and L858R/T790M (IC50=1 nM) EGFR. It addresses resistance to EGFR inhibitors mediated by the T790M mutation in lung cancer.

研究领域

Pharmacology & Drug Discovery

图片与验证

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关键属性

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CAS 号	2564638-97-5
MW	1000.22
分子式	C₅₆H₆₇N₁₄O₄
SMILES	O=C(C=C)NC1=CC(NC=2N=CC=C(N2)C3=CN(C=4C=CC=CC34)C)=C(OC)C=C1N(C)CC[N+](C)(C)CCC(=O)NC5=CC(NC=6N=CC=C(N6)C7=CN(C=8C=CC=CC78)C)=C(OC)C=C5N(C)CCN(C)C
靶点	Others

储存与操作

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储存	-20°C
有效期	12 months from date of receipt.
免责声明	For research use only

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基因符号

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实验方案信息

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