Recombinant p63 Antibody / Rabbit Monoclonal

SKU: orb534114

描述

Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. [UniProt]

研究领域

Apoptotic, Cancer, Developmental Biology, Epigenetics, Neuroscience, Signaling Pathways

图片与验证

−

Item 1 of 1

已测应用	IHC-P
稀释范围	Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
反应性	Human
应用说明	The stated application concentrations are suggested starting points. Titration of the recombinant p63 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

关键属性

−

抗体类型	Primary Antibody
宿主	Rabbit
克隆性	Recombinant
同种型	Rabbit IgG, k
克隆号	TMPR63-1R
免疫原	Full-length human recombinant protein was used as the immunogen for the recombinant p63 antibody.
纯化	Protein A affinity chromatography
偶联	Unconjugated

储存与操作

−

储存	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂	0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
有效期	12 months from date of receipt.
免责声明	For research use only

相似产品

−

Item 1 of 2
Recombinant p63 Antibody / Rabbit Monoclonal [orb606566]
应用：
IHC-P
反应性：
Human, Mouse, Rat
种属/宿主：
Rabbit
克隆性：
Recombinant
偶联：
Unconjugated
可选规格： 100 μg, 20 μg
Item 1 of 2
Recombinant p63 Antibody / Rabbit Monoclonal [orb2641173]
应用：
IHC-P
反应性：
Human, Mouse, Rat
种属/宿主：
Rabbit
克隆性：
Recombinant
偶联：
Unconjugated
可选规格： 100 μg
Item 1 of 1
Recombinant p63 Antibody / Rabbit Monoclonal [orb2641175]
应用：
IHC-P
反应性：
Human
种属/宿主：
Rabbit
克隆性：
Recombinant
偶联：
Unconjugated
可选规格： 100 μg

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

常用数据库链接

UniProt

Q9H3D4

UniProt 详情

−

暂无 UniProt 数据

实验方案信息

IHC-P

石蜡切片免疫组化

查看实验方案

查看更多实验方案

可选规格

请在下方选择规格

20 μg

¥ 4,810.00

100 μg

¥ 9,750.00

选择偶联或无载体版本

免费二抗（20 µl）0/0

请先将抗体产品加入购物车。

数量

Usually dispatched within 5-10 working days

批量询价

需要技术支持？查找经销商退换与税务政策