Pemigatinib (INCB054828)

SKU: orb1220252

描述

Pemigatinib (INCB054828) is an orally active, selective FGFR inhibitor with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.

研究领域

Pharmacology & Drug Discovery

图片与验证

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关键属性

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CAS 号	1513857-77-6
MW	487.5
纯度	>98% (HPLC)
分子式	C??H??F?N?O?
SMILES	CCN(C(N(C(C(F)=C(OC)C=C1OC)=C1F)C2)=O)C(C2=CN3)=C4C3=NC(CN5CCOCC5)=C4
靶点	FGFR
溶解性	DMSO : 25 mg/mL (51.28 mM; ultrasonic and warming and heat to 60°C)

储存与操作

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储存	Storage temperature: -20°C. Stability: ≥ 2 years
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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INCB054828

相似产品

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Pemigatinib [orb1309272]
纯度：
99.95% (May vary between batches)
CAS 号：
1513857-77-6
MW:
487.5
分子式：
C₂₄H₂₇F₂N₅O₄
可选规格： 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 mg, 1 ml x 10 mM (in DMSO)

质量保证

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常用数据库链接

基因符号

FGFR

实验方案信息

查看更多实验方案

纯度：	99.95% (May vary between batches)
CAS 号：	1513857-77-6
MW:	487.5
分子式：	C₂₄H₂₇F₂N₅O₄