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特色
描述
研究领域
Cell Biology
图片与验证
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Item 1 of 5
| 已测应用 | FC, WB |
|---|---|
| 稀释范围 | WB=1:500-2000, Flow-Cyt=1μg /test |
| 反应性 | Human, Mouse, Rat |
| 预测反应性 | Mouse, Rat |
相关偶联物与制剂
−关键属性
−| 抗体类型 | Primary Antibody |
|---|---|
| 宿主 | Rabbit |
| 克隆性 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | KLH conjugated Synthesised phosphopeptide derived from human ASK1 around the phosphorylation site of Thr845 TE(p-T)FT |
| 靶点 | MAP3K5 |
| 分子量 | 155 kDa |
| 纯化 | Affinity purified by Protein A |
| 偶联 | Unconjugated |
储存与操作
−| 储存 | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| 形态/外观 | Liquid |
| 缓冲液/防腐剂 | 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 有效期 | 12 months from date of receipt. |
| 免责声明 | For research use only |
别名
−ASK1; MAPKKK5; MEKK5; 7420452D20Rik; ASK; M3K5_HUMAN; MAP3K5; Apoptosis signal-regulating kinase 1 (ASK-1); MAPK/ERK kinase kinase 5 (MEK kinase 5 | MEKK 5); 2.7.11.25; M3K5_MOUSE; mitogen-activated protein kinase kinase kinase 5; apoptosis signal regulating kinase 1; MAP3K5 | ASK1 (phospho-T845); p-ASK1; phospho-ASK1; p-MAP3K5; MAP3K5 | ASK1 (phospho-Thr845)
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质量保证
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常用数据库链接
基因符号
MAP3K5
UniProt
UniProt 详情
−暂无 UniProt 数据
按应用筛选
按种属筛选
Jiaxuan He 1 2, Siyuan Li 1, Yunpeng Teng 1, Hongfei Xiong 1, Zhuang Wang 1, Xiaoyao Han 1, Wei Gong 2, Ya Gao Increasing expression of dual-specificity phosphatase 12 mitigates oxygen-glucose deprivation/reoxygenation-induced neuronal apoptosis and inflammation through inactivation of the ASK1-JNK/p38 MAPK pathway Autoimmunity, 57, 2345919 (2024)
应用
WB
反应性
Mouse
Chiara Imarisio, Elisa Alchera, Chandrashekar Bangalore Revanna, Guido Valente, Antonia Follenzi, Elena Trisolini, Renzo Boldorini, Rita Carini Oxidative and ER stress-dependent ASK1 activation in steatotic hepatocytes and Kupffer cells sensitizes mice fatty liver to ischemia/reperfusion injury Free Radical Biology and Medicine, 112, 141 (2017)
应用
IHC, WB
反应性
Mouse
