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特色
描述
研究领域
Signal Transduction
图片与验证
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Item 1 of 4
| 已测应用 | IF, IHC-Fr, IHC-P, WB |
|---|---|
| 稀释范围 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 |
| 反应性 | Human, Mouse |
| 预测反应性 | Bovine, Equine, Monkey, Porcine, Sheep |
相关偶联物与制剂
−关键属性
−| 抗体类型 | Primary Antibody |
|---|---|
| 宿主 | Rabbit |
| 克隆性 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | KLH conjugated synthesised phosphopeptide derived from human Parkin around the phosphorylation site of Ser65 QQ(p-S)IV |
| 靶点 | PRKN |
| 分子量 | 50 kDa |
| 纯化 | Affinity purified by Protein A |
| 偶联 | Unconjugated |
储存与操作
−| 储存 | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| 形态/外观 | Liquid |
| 缓冲液/防腐剂 | 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 有效期 | 12 months from date of receipt. |
| 免责声明 | For research use only |
别名
−AR-JP; LPRS2; PARK2; PDJ; PRKN_HUMAN; PRKN; Parkin; Parkin RBR E3 ubiquitin-protein ligase; Parkinson juvenile disease protein 2 (Parkinson disease protein 2); 2.3.2.31; parkin RBR E3 ubiquitin protein ligase; Parkinson disease (autosomal recessive, juvenile) 2, parkin; parkinson protein 2, E3 ubiquitin protein ligase (parkin); E3 ubiquitin ligase; PRKN | Parkin (phospho-S65); p-Parkin; phospho-Parkin; p-PRKN; PRKN | Parkin (phospho-Ser65)
相似产品
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Phospho-Parkin (Ser65) Rabbit Polyclonal Antibody (AP) [orb961896]
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100 μlPhospho-Parkin (Ser65) Rabbit Polyclonal Antibody (APC) [orb1001404]
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100 μlPhospho-Parkin (Ser65) Rabbit Polyclonal Antibody (APC-Cy5.5) [orb2464716]
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质量保证
Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.
常用数据库链接
基因符号
PRKN
UniProt
UniProt 详情
−暂无 UniProt 数据
按应用筛选
按种属筛选
Chakrabarti, Lina et al. Mitochondrial membrane potential-enriched CHO host: a novel and powerful tool for improving biomanufacturing capability MAbs, 14, 2020081 (2022)
Jamie Whitfield 1, Alannah K A McKay 2, Nicolin Tee 2, Rachel McCormick 2, Aimee Morabito 2, Leonidas G Karagounis 2 3 4, Andréane M Fouassier 5, Davide D'Amico 5, Anurag Singh 5, Louise M Burke 2, John A Hawley 2 6 Evaluating the Impact of Urolithin A Supplementation on Running Performance, Recovery, and Mitochondrial Biomarkers in Highly Trained Male Distance Runners Sports Medicine, (2025)
应用
WB
反应性
Human
Huang, Yi-Fan et al. The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury FASEB J, 34, 2055-2074 (2020)
Yu, Shao-Hua et al. Human antigen R regulates hypoxia-induced mitophagy in renal tubular cells through PARKIN/BNIP3L expressions J Cell Mol Med, 25, 2691-2702 (2021)
Lane, Sydney L. et al. Increased Systemic Antioxidant Power Ameliorates the Aging-Related Reduction in Oocyte Competence in Mice Int J Mol Sci, 22, 13019 (2021)
Sun, Xin et al. Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy Acta Pharm Sin B, 12, 838-852 (2022)
Zhang, Qin et al. Regulation of mitophagy through HIF-1?/miR-140-5p/PARKIN axis in acute kidney injury Environ Toxicol, 37, 1759-1767 (2022)
Rai, Rajani et al. Distinct mechanism of cervical cancer cell death caused by the investigational new drug SHetA2 Front Oncol, 12, 958536 (2022)
应用
IHC
反应性
Porcine
Singh, Anurag et al. Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults Cell Rep Med, 3, 100633 (2022)
Chao, Tony et al. Burn-Induced Reductions in Mitochondrial Abundance and Efficiency are More Pronounced with Small Volumes of Colloids in Swine Am. J. Physiol., Cell Physiol., (2019)
