Picroside IV

SKU: orb1684315

描述

Picroside IV, a catalpol-derived iridoid glycoside from Picrorhiza scrophulariiflora, exhibits diverse pharmacological activities such as neuroprotection and anti-inflammatory effects. It is a valuable research compound for in vitro and in vivo studies in neuroscience, oncology, and metabolic disease research.

研究领域

Infectious Disease & Virology

图片与验证

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关键属性

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CAS 号	211567-04-3
MW	508.47
纯度	99.92% (May vary between batches)
分子式	C₂₄H₂₈O₁₂
SMILES	C(O)[C@@]12[C@@](O1)([C@@H](O)[C@]3([C@@]2([C@H](O[C@@H]4O[C@H](COC(/C=C/C5=CC=C(O)C=C5)=O)[C@@H](O)[C@H](O)[C@H]4O)OC=C3)[H])[H])[H]
靶点	HBV
溶解性	DMSO:80 mg/mL (157.33 mM)

生物活性

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体外

The pharmacokinetic results indicated that the six components (picroside I, picroside II, vanillic acid, androsin, cinnamic acid, and Picroside IV) in TGPR could be quickly absorbed and slowly eliminated. Their bioavailability was less than 12.37%, indicating poor absorption after intragastric dosing. For tissue distribution, the six components in TGPR were detected in the liver, and only androsin could penetrate the blood-brain barrier. Meanwhile, the excretion study demonstrated that vanillic acid was mostly excreted as prototype drugs, and the remaining five components might be widely metabolized in vivo as the metabolites; the unconverted form was excreted mainly by the feces route .

储存与操作

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储存	-20°C
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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Picroside IV

质量保证

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化合物标识

PubChem CID

23928135 ↗

关键属性

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暂无计算属性。

实验方案信息

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Picroside IV

描述

研究领域

图片与验证

关键属性

生物活性

储存与操作

别名

质量保证

化合物标识

关键属性

实验方案信息

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