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PU.1 Antibody / SPI1

SKU: orb2637048

描述

PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development.

研究领域

Stem Cell & Developmental Biology

图片与验证

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已测应用IHC-P
稀释范围Immunohistochemistry (FFPE): 1-2ug/ml
反应性Human
应用说明
Optimal dilution of the PU.1 antibody should be determined by the researcher.

关键属性

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抗体类型Primary Antibody
宿主Mouse
克隆性Monoclonal
同种型Mouse IgG1
克隆号PU1/2118
免疫原A portion of amino acids 16-170 was used as the immunogen for the PU.1 antibody.
纯化Protein A/G affinity
偶联Unconjugated

储存与操作

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储存Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
有效期12 months from date of receipt.
免责声明For research use only

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质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

UniProt 详情

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暂无 UniProt 数据

实验方案信息

IHC-P
石蜡切片免疫组化
查看实验方案

可选规格

请在下方选择规格

100 μg
¥ 9,750.00
选择偶联或无载体版本
免费二抗(20 µl)0/0

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发货Usually dispatched within 5-10 working days
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