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RdRP-IN-9

SKU: orb2945667

描述

RdRP-IN-9 (Compound 6b) is a reversible covalent allosteric RdRp inhibitor that acylates Cys12 in the nsp12 NiRAN domain. It exhibits potent antiviral activity against HCoV-OC43 (EC50 = 0.68 µM) and demonstrates synergistic effects with Molnupiravir in vitro, supporting its use in coronavirus research and antiviral development.

研究领域

Infectious Disease & Virology

图片与验证

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关键属性

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CAS 号1101848-34-3
MW343.374
分子式C19H21NO5
SMILESO(C(CC)=O)[C@H]1[C@@]2([C@@]3(N(CC=4C2=CC5=C(C4)OCO5)CCC3=C[C@@H]1O)[H])[H]
靶点SARS-CoV

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only
质量保证

质量保证

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关键属性

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实验方案信息

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50 mg
10 mg