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SF1126

SKU: orb1706641

描述

SF1126 is a first-in-class, pan and dual PI3K/BRD4 inhibitor developed as an RGDS-conjugated prodrug of LY294002. This design enhances solubility and promotes tumor-targeted delivery via integrin binding. It has demonstrated activity in both in vitro and in vivo cancer models, including studies in multiple myeloma and solid tumors.

研究领域

Cell Biology, Signal Transduction

图片与验证

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关键属性

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CAS 号936487-67-1
MW852.84
分子式C39H48N8O14
SMILESC(OC(CCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(O)=O)CO)=O)CC([O-])=O)=O)=O)CCCNC(=N)N)=O)=O)[N+]1(CCOCC1)C=2OC3=C(C=CC=C3C(=O)C2)C4=CC=CC=C4
靶点Apoptosis,PI3K,Others

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only

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质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

关键属性

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实验方案信息

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25 mg