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SP 600125, negative control

SKU: orb1692168

描述

SP 600125 negative control is a methylated analog serving as a negative control for the JNK inhibitor SP 600125. It inhibits the DTP3 and GADD45β/MKK7 complex, restoring pathway activation, and exhibits IC50 values of 18 μM and 24 μM against JNK2 and JNK3, respectively. This compound is a valuable tool for validating JNK-related signaling mechanisms in both cellular and biochemical assays.

研究领域

Cell Biology, Signal Transduction

图片与验证

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关键属性

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CAS 号54642-23-8
MW234.25
纯度99.89% (May vary between batches)
分子式C15H10N2O
SMILESO=C1C=2C=3C(C=4C1=CC=CC4)=NN(C)C3C=CC2
靶点Apoptosis,Autophagy,Others,JNK,Ferroptosis
溶解性DMSO:9 mg/mL (38.42 mM)

生物活性

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靶点 IC50
TrkB:0.899 µM

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only

别名

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GADD45β/MKK7, JNK3, JNK Inhibitor II, negative control, JNK2, SP 600125, negative control

相似产品

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  • SP 600125, negative control [orb2900967]

    >98% (HPLC)

    54642-23-8

    234.25

    C15H10N2O

    50 mg, 100 mg, 500 mg, 1 g, 5 mg, 10 mg, 25 mg
质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

关键属性

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暂无计算属性。

实验方案信息

可选规格

请在下方选择规格

10 mg
¥ 1,040.00
25 mg
¥ 1,560.00
50 mg
¥ 2,080.00
100 mg
¥ 2,860.00
500 mg
¥ 5,980.00
发货Usually dispatched within 5-10 working days
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