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SuO-Val-Cit-PAB-MMAE

SKU: orb1987698

描述

This ADC linker incorporates the cytotoxic payload MMAE, a potent tubulin inhibitor, via a protease-cleavable SuO-Val-Cit-PAB peptide sequence. It is widely used in the development of antibody-drug conjugates for targeted cancer therapy research, enabling the study of drug delivery and efficacy in both in vitro and in vivo models.

研究领域

Pharmacology & Drug Discovery, Signal Transduction

图片与验证

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关键属性

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MW1264.51
分子式C63H97N11O16
SMILESCC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(ON4C(CCC4=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C
靶点PROTAC Linker,Drug-Linker Conjugates for ADC

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only

相似产品

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  • SuO-Val-Cit-PAB-MMAE [orb2647144]

    0.98

    1264.508

    C63H97N11O16

    100 mg
质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

关键属性

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实验方案信息

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100 mg
500 mg