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Suvorexant
描述
研究领域
图片与验证
−关键属性
−| CAS 号 | 1030377-33-3 |
|---|---|
| MW | 450.9207 |
| 分子式 | C23H23CLN6O2 |
| SMILES | ClC1C([H])=C([H])C2=C(C=1[H])N=C(N1C([H])([H])C([H])([H])N(C(C3C([H])=C(C([H])([H])[H])C([H])=C([H])C=3N3N=C([H])C([H])=N3)=O)[C@]([H])(C([H])([H])[H])C([H])([H])C1([H])[H])O2 |
储存与操作
−| 储存 | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
|---|---|
| 有效期 | 12 months from date of receipt. |
| 免责声明 | For research use only |
别名
−相似产品
−4-((2-Aminoethyl)(5-chlorobenzo[d]oxazol-2-yl)amino)butan-2-one dimethanesulfonate [orb3143887]
1276666-12-6
377.84
C14H20ClN3O5S
10 mg, 50 mg

质量保证
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化合物标识
关键属性
−实验方案信息
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按种属筛选
Hiroki Endo et al. Dexamethasone induces sleep disruption in male mice and is associated with hyperactivation of orexin neurons Psychopharmacology (Berl) ., (2026)
Rupinder Kaur Sodhi et al. Suvorexant protects from ocular complications of diabetes in db/db mice BMJ Open Diabetes Res Care, (2026)
反应性
Carlos Carrera-Cañas 1, Isabel de Andrés 1, Marta Callejo 1, Miguel Garzón 2 Hypocretin/orexin peptide release occurs mostly extrasynaptically, is self-controlled, and specifically enhanced in female rats Exp Neurol, (2025)
Gun Young Yoon et al. Disruption of the hypothalamic orexin system links SARS-CoV-2 infection to persistent cortical neuronal pathology bioRxiv, (2026)
Khoa Nguyen Tran et al. Orexinergic modulation by Uwhangchungsimwon restores homeostasis of GABA/BDNF signaling in insomnia-depression comorbidity J Ethnopharmacol, (2026)
应用
反应性


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