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TLR4 Antibody (PerCP)

SKU: orb152206
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描述

Rabbit polyclonal to TLR4 (PerCP). The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling (4,5). The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90kDa..

研究领域

Immunology & Inflammation

图片与验证

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已测应用FACS, FC, ICC, IF, IHC, WB
稀释范围WB (1:500), IHC (1:50)
反应性Human, Mouse
应用说明
2 µg/ml was sufficient for detection of TLR4 in 100 ng of partial recombinant mouse TLR4 protein by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

关键属性

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宿主Rabbit
克隆性Polyclonal
免疫原Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4
靶点TLR4
分子量75-80kDa
纯化Protein A Purified
偶联PerCP

储存与操作

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储存Conjugated antibodies should be stored according to the product label
缓冲液/防腐剂95.46mM Phosphate, 2.48mM MES and 2mM EDTA
浓度1 mg/ml
有效期12 months from date of receipt.
免责声明For research use only

别名

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ARMD10, CD284, TLR 4, TOLL, Toll like receptor 4

相似产品

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质量保证

质量保证

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常用数据库链接

基因符号
TLR4
UniProt
O00206
NCBI 基因 ID
7099
RefSeq（蛋白）：NP_612564.1

UniProt 详情

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暂无 UniProt 数据

NCBI 基因详情

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暂无 NCBI 基因数据

NCBI 参考序列

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相关登录号
基因转录本和蛋白产物的整理参考序列
蛋白NP_612564.1

实验方案信息

WB
免疫印迹（WB）
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IHC
免疫组化
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FACS
荧光激活细胞分选（FACS，流式细胞术）
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FC
流式细胞术
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IF
免疫荧光
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ICC
免疫细胞化学
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可选规格

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100 μg
¥ 7,930.00
选择偶联或无载体版本
免费二抗（20 µl）0/0

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发货Usually dispatched within 2-3 weeks
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