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Y-27632 2HCL

SKU: orb154626

描述

Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM.

图片与验证

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关键属性

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CAS 号129830-38-2
MW320.26
分子式C14H23Cl2N3O
SMILESC[C@H](C1CCC(CC1)C(=O)NC2=CC=NC=C2)N.Cl.Cl

储存与操作

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储存Can be stored for 2 years at -20°C in powder form, 2 weeks at 4°C in DMSO, and 6 months at -80°C in DMSO.
有效期12 months from date of receipt.
危害信息Non-Toxic
免责声明For research use only

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质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

实验方案信息

按应用筛选

按种属筛选

Barbora Schwarzova, Tim Studemann, Muhammed Sonmez, Judith Rossinger, Bangfen Pan, Thomas Eschenhagen, Justus Stenzig, J. Simon Wiegert, Torsten Christ & Florian Weinberger Modulating cardiac physiology in engineered heart tissue with the bidirectional optogenetic tool BiPOLES Pflugers Arch., (2023)

应用

Cell Culture

反应性

Human

Karl T Wagner 1, Rick X Z Lu 1, Shira Landau 1, Sarah A Shawky 2, Yimu Zhao 1, David F Bodenstein 1, Luis Felipe Jiménez Vargas 1, Richard Jiang 3, Sargol Okhovatian 1, Ying Wang 1, Chuan Liu 1, Daniel Vosoughi 4, Dakota Gustafson 4, Jason E Fish 5, Carolyn L Cummins 6, Milica Radisic 1 Endothelial extracellular vesicles enhance vascular self-assembly in engineered human cardiac tissues Biofabrication, (2024)

J Raabe, I Wittig, P Laurette, K Stathopoulou, T Brand Physioxia rewires mitochondrial complex composition to protect stem cell viability Redox Biology, (2024)

Mireia Nàger 1, Kenneth B Larsen 2 3, Zambarlal Bhujabal 2, Trine B Kalstad 2, Judith Rössinger 4, Truls Myrmel 1 2, Florian Weinberger 4 5, Asa B Birgisdottir Mitophagy is induced in human engineered heart tissue after simulated ischemia and reperfusion J Cell Sci ., (2025)

Anca Kliesow Remes # 1 2, Theresa Ruf # 3 4, Tinatin Zurashvili 1 5, Lin Ding 3 6, Moritz Meyer-Jens 2 7, Dominic M Schwab 3, Susanne Hille 1 2, Andrea Matzen 2 6, Sabine Michalewski 1 2, Lucia Kilian 2 6, Prithviraj Manohar Vijaya Shetty 1 2, Marie-Christin Fuchs 3, Matthias Eden 3 4 6, Hermann-Josef Gröne 8, Kleopatra Rapti 3, Andreas Jungmann 3, Hendrik Milting 9, Hugo A Katus 3 4, Lucie Carrier 2 7, Derk Frank 2 6, Norbert Frey 3 4, Oliver J Müller AAV-mediated overexpression of CPT1B protects from cardiac hypertrophy and heart failure in a murine pressure overload model Basic Res Cardiol, (2025)

应用

Cell Culture

反应性

Human

Nancy Sorial Samy Shehata Evidence for the inhibition of cardiomyocytes cycle activity by cardiac contraction Natural Sciences University of Hamburg, (2026)

应用

Cell Culture

应用

Cell Culture

反应性

Human

可选规格

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100 mg
¥ 9,750.00
250 mg
¥ 17,160.00
1 g
¥ 33,670.00
发货Usually dispatched within 5-10 working days
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