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Y-27632 HCl hydrate

SKU: orb1740051

描述

Y-27632 HCl hydrate is an orally active, ATP-competitive inhibitor of ROCK1/ROCK2. It inhibits caspase-3 activity and suppresses stem cell apoptosis, making it a valuable reagent for improving the survival and generation efficiency of induced pluripotent stem cells (iPSCs) in both in vitro culture and in vivo transplantation studies.

研究领域

Cell Biology, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology

图片与验证

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关键属性

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CAS 号331752-47-7
MW338.27
纯度99.98% (May vary between batches)
分子式C14H25Cl2N3O2
SMILESO=C([C@H]1CC[C@](CC1)([H])[C@H](N)C)NC2=CC=NC=C2.Cl.O.Cl
靶点Caspase,ROCK,Apoptosis

生物活性

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靶点 IC50
ROCK2:300 nM (Ki)|ROCK1:220 nM (Ki)

储存与操作

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储存-20°C
有效期12 months from date of receipt.
免责声明For research use only

别名

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Y 27632, Y27632, Y-27632, Y27632 hydrochloride hydrate
质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

关键属性

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暂无计算属性。

实验方案信息

可选规格

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25 mg
1 mg
¥ 910.00
5 mg
¥ 1,820.00
10 mg
¥ 2,470.00