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描述
研究领域
Cancer Biology, Cell Biology, Epigenetics & Chromatin, Metabolism Research, Protein Biochemistry, Signal Transduction
图片与验证
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Item 1 of 5
| 已测应用 | FC, ICC, IF, IHC, IP, WB |
|---|---|
| 稀释范围 | WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:50 FC 1:50 |
| 反应性 | Human, Mouse, Rat |
关键属性
−| 抗体类型 | Primary Antibody |
|---|---|
| 宿主 | Rabbit |
| 克隆性 | Monoclonal |
| 同种型 | Rabbit IgG |
| 克隆号 | BGDIX3 |
| 免疫原 | A synthesized peptide derived from human AKT1 Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473. |
| 靶点 | RAC-alpha serine/threonine-protein kinase |
| 分子量 | 56 kDa |
| 纯化 | Affinity-chromatography |
| 偶联 | Unconjugated |
储存与操作
−| 储存 | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| 形态/外观 | Liquid |
| 缓冲液/防腐剂 | Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required. |
| 浓度 | 0.5mg/ml |
| 有效期 | 12 months from date of receipt. |
| 免责声明 | For research use only |
别名
−Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF
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质量保证
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常用数据库链接
基因符号
RAC-alpha serine/threonine-protein kinase
UniProt
UniProt 详情
−暂无 UniProt 数据
