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描述
研究领域
Cancer Biology, Cardiovascular Research, Cell Biology, Disease Biomarkers, Epigenetics & Chromatin, Neuroscience, Stem Cell & Developmental Biology
图片与验证
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Item 1 of 2
| 已测应用 | ICC, IF, IHC, IP, WB |
|---|---|
| 稀释范围 | WB 1:500-2000 IHC 1:50-200 ICC/IF 1:50-200 IP 1:20 |
| 反应性 | Human, Mouse, Rat |
关键属性
−| 抗体类型 | Primary Antibody |
|---|---|
| 宿主 | Rabbit |
| 克隆性 | Monoclonal |
| 同种型 | Rabbit IgG |
| 克隆号 | BHCFX3 |
| 免疫原 | A synthesized peptide derived from human APC Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. |
| 靶点 | Adenomatous polyposis coli protein |
| 分子量 | 160 kDa |
| 纯化 | Affinity-chromatography |
| 偶联 | Unconjugated |
储存与操作
−| 储存 | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
|---|---|
| 形态/外观 | Liquid |
| 缓冲液/防腐剂 | Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required. |
| 浓度 | 0.5mg/ml |
| 有效期 | 12 months from date of receipt. |
| 免责声明 | For research use only |
别名
−Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3; APRF
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质量保证
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常用数据库链接
基因符号
Adenomatous polyposis coli protein
UniProt
UniProt 详情
−暂无 UniProt 数据
