Aucubin

SKU: orb1222210

描述

Aucubin is an iridoid glycoside. Iridoids are commonly found in plants and function as defensive compounds. Irioids decrease the growth rates of many generalist herbivores. Aucubin was found to protect against liver damage induced by carbon tetrachloride or alpha-amanitin in mice and rats when 80 mg/kg was dosed intraperitoneally.

图片与验证

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关键属性

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CAS 号	479-98-1
MW	346.33
纯度	>98% (HPLC)
分子式	C₁₅H₂₂O₉
SMILES	C1=CO[C@H]([C@H]2[C@@H]1[C@@H](C=C2CO)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
靶点	IL-1β\| NF-κB
溶解性	DMSO : ≥ 31 mg/mL; 89.51 mM

生物活性

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体内

Animal model: Male Wistar rats (200-230 g) induced diabetes by a injection of streptozotocin. Dosage: 5 mg/kg. Administration: i.p. twice daily for the first 5 days, followed by single injections daily for the last 10 days. Result: Increased the body weight of streptozotocin-diabetic rats. Lowered the blood glucose level. Decreased the level of lipid peroxidation and increased the activities of antioxidant enzymes. Increased in insulin immunoreactivity and the number of immunoreactive β cells compared with untreated diabetic rats.

储存与操作

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储存	Storage temperature: -20°C. Stability: ≥ 2 years
有效期	12 months from date of receipt.
免责声明	For research use only

相似产品

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Aucubin [orb1304221]
纯度：
99.83% (May vary between batches)
CAS 号：
479-98-1
MW:
346.33
分子式：
C₁₅H₂₂O₉
可选规格： 250 mg, 500 mg, 1 g
Catalpol [orb1225547]
纯度：
>98% (HPLC)
CAS 号：
2415-24-9
MW:
362.33
分子式：
C₁₅H₂₂O₁₀
可选规格： 50 mg, 100 mg, 200 mg, 500 mg, 1 g, 10 mg, 25 mg

质量保证

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常用数据库链接

基因符号

IL-1β| NF-κB

实验方案信息

查看更多实验方案

纯度：	99.83% (May vary between batches)
CAS 号：	479-98-1
MW:	346.33
分子式：	C₁₅H₂₂O₉