Catalpol

SKU: orb1225547

描述

Catalpol, an iridoid glycoside, has neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.(In Vitro):Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length.(In Vivo):Catalpol (25-100 mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities.

图片与验证

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关键属性

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CAS 号	2415-24-9
MW	362.33
纯度	>98% (HPLC)
分子式	C₁₅H₂₂O₁₀
SMILES	[H][C@]1([C@H](O)[C@@]2([H])[C@]3(CO)O2)[C@]3([H])[C@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)OC=C1
靶点	Others
溶解性	DMSO: 10 mM

生物活性

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体内

Catalpol (25-100 mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities. Animal model: C57BL/6 mice treated with renal ischemia/reperfusion surgery. Dosage: 25 mg/kg, 50 mg/kg and 100 mg/kg. Administration: Intraperitoneal injection; once. Result: Clearly reduced blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal IRI mice.

体外

Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length.

储存与操作

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储存	Storage temperature: -20°C. Stability: ≥ 2 years
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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Catalpinoside | 7,8-epoxy Aucubin

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纯度：
99.89% (May vary between batches)
CAS 号：
2415-24-9
MW:
362.33
分子式：
C₁₅H₂₂O₁₀
可选规格： 1 ml x 10 mM (in DMSO), 500 mg, 50 mg, 25 mg, 100 mg
Picroside II [orb1304982]
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Catalposide [orb1682985]
纯度：
99.82% (May vary between batches)
CAS 号：
6736-85-2
MW:
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分子式：
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可选规格： 1 mg, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

常用数据库链接

基因符号

Others

实验方案信息

查看更多实验方案

纯度：	99.89% (May vary between batches)
CAS 号：	2415-24-9
MW:	362.33
分子式：	C₁₅H₂₂O₁₀

纯度：	99.83% (May vary between batches)
CAS 号：	39012-20-9
MW:	512.461
分子式：	C₂₃H₂₈O₁₃

纯度：	99.92% (May vary between batches)
CAS 号：	211567-04-3
MW:	508.47
分子式：	C₂₄H₂₈O₁₂

纯度：	99.82% (May vary between batches)
CAS 号：	6736-85-2
MW:	482.43
分子式：	C₂₂H₂₆O₁₂

Catalpol

描述

图片与验证

关键属性

生物活性

储存与操作

别名

相似产品

Rehmannia root extract [orb3212123]

Catalpol [orb1305028]

Picroside II [orb1304982]

Picroside IV [orb1684315]

Catalposide [orb1682985]

质量保证

常用数据库链接

实验方案信息

可选规格