C-82

SKU: orb1940817

描述

C-82 is a specific CBP/β-catenin antagonist. It inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300.(In Vitro):C-82 inhibits the activation of isolated primary mouse quiescent hepatic stellate cells (HSCs) and promotes cell death in culture-activated HSCs.(In Vivo):PRI-724 is phosphorylated-C-82 and is rapidly hydrolyzed to its active form C-82 in vivo, and pre-clinical studies have shown a very acceptable toxicity profile.

图片与验证

−

关键属性

−

CAS 号	1422253-37-9
MW	578.673
纯度	>98% (HPLC)
分子式	C₃₃H₃₄N₆O₄
SMILES	[H][C@]12[C@H](C)N(Cc3cccc4cccnc34)C(=O)[C@H](Cc3ccc(O)cc3)N1C(=O)CN(C)N2C(=O)NCc1ccccc1
靶点	Epigenetic Reader Domain

储存与操作

−

储存	Storage temperature: -20°C. Stability: ≥ 2 years
有效期	12 months from date of receipt.
免责声明	For research use only

相似产品

−

PRI-724 [orb1685665]
纯度：
99.11% (May vary between batches)
CAS 号：
1422253-38-0
MW:
658.64
分子式：
C₃₃H₃₅N₆O₇P
可选规格： 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)
C-82 [orb1309889]
纯度：
99.72% (May vary between batches)
CAS 号：
1422253-37-9
MW:
578.66
分子式：
C₃₃H₃₄N₆O₄
可选规格： 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO)

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

常用数据库链接

基因符号

Epigenetic Reader Domain

实验方案信息

查看更多实验方案

纯度：	99.11% (May vary between batches)
CAS 号：	1422253-38-0
MW:	658.64
分子式：	C₃₃H₃₅N₆O₇P

纯度：	99.72% (May vary between batches)
CAS 号：	1422253-37-9
MW:	578.66
分子式：	C₃₃H₃₄N₆O₄