CD137 Antibody / 4-1BB / TNFRSF9

SKU: orb2642858

描述

CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.

研究领域

Immunology & Inflammation

图片与验证

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已测应用	IHC-P
稀释范围	The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
反应性	Human
应用说明	Optimal dilution of the CD137 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

关键属性

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抗体类型	Primary Antibody
宿主	Mouse
克隆性	Monoclonal
同种型	Mouse IgG1, kappa
克隆号	4-1BB/3201
免疫原	A recombinant human CD137 protein fragment within amino acids 19-188 was used as the immunogen for the CD137 antibody.
纯化	Protein G affinity chromatography
偶联	Unconjugated

储存与操作

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储存	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂	Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only
有效期	12 months from date of receipt.
免责声明	For research use only

相似产品

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CD137 Antibody / 4-1BB / TNFRSF9 [orb607142]
应用：
ELISA, FACS, IF, IHC-P, WB
反应性：
Human
种属/宿主：
Mouse
克隆性：
Monoclonal
偶联：
Unconjugated
可选规格： 20 μg, 100 μg
Item 1 of 8
CD137 Antibody / 4-1BB / TNFRSF9 [orb2642859]
应用：
ELISA, FACS, IF, IHC-P, WB
反应性：
Human
种属/宿主：
Mouse
克隆性：
Monoclonal
偶联：
Unconjugated
可选规格： 100 μg
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Recombinant CD137 Antibody / 4-1BB / TNFRSF9 [orb639906]
应用：
IHC-P, WB
反应性：
Human
种属/宿主：
Mouse
克隆性：
Recombinant
偶联：
Unconjugated
可选规格： 20 μg, 100 μg
Item 1 of 2
Recombinant CD137 Antibody / 4-1BB / TNFRSF9 [orb699703]
应用：
IHC-P
反应性：
Human
种属/宿主：
Mouse
克隆性：
Recombinant
偶联：
Unconjugated
可选规格： 20 μg, 100 μg
Item 1 of 2
CD137 Antibody / 4-1BB / TNFRSF9 [orb607111]
应用：
IF, IHC-P
反应性：
Human
种属/宿主：
Mouse
克隆性：
Monoclonal
偶联：
Unconjugated
可选规格： 20 μg, 100 μg

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

常用数据库链接

UniProt

Q07011

UniProt 详情

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暂无 UniProt 数据

实验方案信息

IHC-P

石蜡切片免疫组化

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应用：	ELISA, FACS, IF, IHC-P, WB
反应性：	Human
种属/宿主：	Mouse
克隆性：	Monoclonal
偶联：	Unconjugated

应用：	IHC-P, WB
反应性：	Human
种属/宿主：	Mouse
克隆性：	Recombinant
偶联：	Unconjugated