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CD137 Antibody / 4-1BB / TNFRSF9

SKU: orb607111

描述

CD137 belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. It is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. CD137 antibody may improve cancer treatment, and has been implicated in breast cancer, melanoma and lymphoma.

研究领域

Immunology & Inflammation

图片与验证

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已测应用IF, IHC-P
稀释范围Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
反应性Human
应用说明
Optimal dilution of the CD137 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

关键属性

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抗体类型Primary Antibody
宿主Mouse
克隆性Monoclonal
同种型Mouse IgG1, kappa
克隆号CDLA137-1
免疫原A recombinant human CD137 protein fragment within amino acids 19-188 was used as the immunogen for the CD137 antibody.
纯化Protein G affinity chromatography
偶联Unconjugated

储存与操作

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储存Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
缓冲液/防腐剂0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
有效期12 months from date of receipt.
免责声明For research use only

相似产品

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质量保证

质量保证

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our 条款与条件和选购指南.

UniProt 详情

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暂无 UniProt 数据

实验方案信息

IHC-P
石蜡切片免疫组化
查看实验方案
IF
免疫荧光
查看实验方案

可选规格

请在下方选择规格

20 μg
¥ 4,810.00
100 μg
¥ 9,750.00
选择偶联或无载体版本
免费二抗(20 µl)0/0

请先将抗体产品加入购物车。

发货Usually dispatched within 5-10 working days
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