Molnupiravir

SKU: orb1689082

描述

Molnupiravir (EIDD-2801) is an orally bioavailable prodrug of the antiviral ribonucleoside EIDD-1931. It is a broad-spectrum antiviral research compound active against SARS-CoV-2, influenza, and other coronaviruses in both in vitro and in vivo experimental models.

研究领域

Infectious Disease & Virology

图片与验证

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关键属性

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CAS 号	2492423-29-5
MW	329.31
纯度	99.81% (May vary between batches)
分子式	C₁₃H₁₉N₃O₇
SMILES	CC(C)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc\c(=N/O)[nH]c1=O
靶点	Influenza Virus,SARS-CoV
溶解性	10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.07 mM);DMSO:257.5 mg/mL (781.94 mM)

生物活性

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体内

METHODS: Molnupiravir (MK-4482) (EIDD-2801) (50, 150, or 500 mg/kg, orally, every 12 hours) was used to prophylactically treat mice infected with SARS-CoV and observe its effects in mice. RESULTS Molnupiravir has potent antiviral activity and is able to prevent SARS-CoV replication and disease.

体外

METHODS: RD, Huh7, and Vero cells were treated with Molnupiravir (MK-4482) (EIDD-2801) (1, 10, 100 μM) for cytopathic effect (CPE) protection assay. RESULTS EIDD-2801 showed stable CPE protection potential in a dose-dependent manner in multiple cell lines infected with EV-A71 virus; the value against EV-A71 virus was 70.12±4.40μM in RD cells; 88.52±3.18μM in Vero cells, and 35.64±0.47μM in Huh7 cells.

储存与操作

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储存	-20°C
有效期	12 months from date of receipt.
免责声明	For research use only

别名

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2349386-89-4, Molnupiravir, MK4482, MK-4482, MK 4482, InfluenzaVirus, Influenza virus, Influenza Virus, Lagevrio, EIDD 2801, EIDD2801, EIDD-2801, SARSCoV, SARS-CoV

相似产品

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Item 1 of 1
EIDD-2801 [orb1090019]
纯度：
≥98%
CAS 号：
2349386-89-4, 2492423-29-5
MW:
329.3
可选规格： 5 mg, 10 mg, 25 mg, 100 mg
N-Butyl molnupiravir [orb3180079]
CAS 号：
2770244-32-9
MW:
329.31
分子式：
C₁₃H₁₉N₃O₇
可选规格： 10 mg, 50 mg
RdRP-IN-9 [orb2945667]
CAS 号：
1101848-34-3
MW:
343.374
分子式：
C₁₉H₂₁NO₅
可选规格： 50 mg, 10 mg
EIDD-2801 [orb1299050]
纯度：
>99.99% (May vary between batches)
CAS 号：
2349386-89-4
MW:
329.31
分子式：
C₁₃H₁₉N₃O₇
可选规格： 10 mg, 25 mg, 50 mg, 100 mg, 500 mg, 1 g, 5 mg, 200 mg, 1 ml x 10 mM (in DMSO)

质量保证

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化合物标识

PubChem CID

145996610 ↗

关键属性

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暂无计算属性。

实验方案信息

查看更多实验方案

CAS 号：	2770244-32-9
MW:	329.31
分子式：	C₁₃H₁₉N₃O₇

CAS 号：	1101848-34-3
MW:	343.374
分子式：	C₁₉H₂₁NO₅

纯度：	>99.99% (May vary between batches)
CAS 号：	2349386-89-4
MW:	329.31
分子式：	C₁₃H₁₉N₃O₇

Molnupiravir

描述

研究领域

图片与验证

关键属性

生物活性

储存与操作

别名

相似产品

EIDD-2801 [orb1090019]

N-Butyl molnupiravir [orb3180079]

RdRP-IN-9 [orb2945667]

EIDD-2801 [orb1299050]

质量保证

化合物标识

关键属性

实验方案信息

可选规格